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Intoxication by 3-MeO-PCP and O-desmethyltramadol: an unusual NPS mix

2022-04-01Artigo científico Acesso aberto
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dc.contributor.authorCastro, André Lobo
dc.contributor.authorCarneiro De Sousa Pinto Costa, Maria José
dc.contributor.authorTarelho, Sónia
dc.contributor.authorSousa, Lara
dc.contributor.authorRusso, Fernando
dc.contributor.authorFranco, João Miguel
dc.date.accessioned2023-02-09T12:05:16Z
dc.date.available2023-04-01T00:30:34Z
dc.date.issued2022-04-01
dc.description.abstractOver the past few years, the new psychoactive substances’ phenomenon has been continuously studied. Its dynamic context is characterized by a broad diversity of substances, including several groups, such as synthetic cathinones, synthetic opiates, and synthetic cannabinoids. However, and due both to this diversity and to the low number of detected cases, information on intoxication reports is always important, in order to understand their biological mechanisms. In this case, a male individual was found unresponsive, with some different powders and paraphernalia near him. After toxicological analysis to the powders, paraphernalia, and whole blood samples, five different compounds were identified. From these, two of them (3-MeO-PCP and o-desmethyltramadol) were identified and quantitated in the whole blood sample. The obtained results suggested that death was due to the presence and action of these two substances, in what may be considered an unusual mix of NPS. This case highlights the value of evaluating all the traces found in the scene investigation and the need of sending all the paraphernalia found for toxicological examination, together with all the possible information obtained on the scene, namely by relatives or witnesses. On the other hand, this case shows the significance of broad-spectrum analytical methods, in order to detect and identify, as specifically as possible, eventual substances present and used by victims.pt_PT
dc.description.versioninfo:eu-repo/semantics/acceptedVersionpt_PT
dc.identifier.citationCastro, A.L., da Costa, M.J.C.S.P., Tarelho, S. et al. Intoxication by 3-MeO-PCP and O-desmethyltramadol: an unusual NPS mix. Int J Legal Med 136, 1297–1301 (2022).pt_PT
dc.identifier.doihttps://doi.org/10.1007/s00414-022-02818-wpt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/43754
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherSpringer Linkpt_PT
dc.relation.publisherversionhttps://link.springer.com/article/10.1007/s00414-022-02818-wpt_PT
dc.subjectO-desmethyl tramadolpt_PT
dc.subject3-MeO-PCPpt_PT
dc.subjectIntoxicationpt_PT
dc.subjectForensic Toxicologypt_PT
dc.titleIntoxication by 3-MeO-PCP and O-desmethyltramadol: an unusual NPS mixpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.endPage1301pt_PT
oaire.citation.startPage1297pt_PT
oaire.citation.titleInternational Journal of Legal Medicinept_PT
oaire.citation.volume136pt_PT
person.familyNameLobo Castro
person.familyNameCarneiro de Sousa Pinto Costa
person.familyNameTarelho
person.familyNameFranco
person.givenNameAndré
person.givenNameMaria José
person.givenNameSónia
person.givenNameJoão
person.identifier.orcid0000-0002-7258-8523
person.identifier.orcid0000-0003-2439-529X
person.identifier.orcid0000-0001-8366-6702
person.identifier.orcid0000-0002-3268-3841
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationfedcfeb0-e610-4375-aa1e-5ac1fa74cd28
relation.isAuthorOfPublication73822617-7855-40b5-a21b-03a7a20cfcd1
relation.isAuthorOfPublication631cbcb7-4c75-4fc1-b4cf-8445d428f1de
relation.isAuthorOfPublication045c4125-1313-445f-b05f-b7f204886052
relation.isAuthorOfPublication.latestForDiscovery045c4125-1313-445f-b05f-b7f204886052

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