Repository logo
 
Publication

Atrial fibrillation and early vascular aging: clinical implications, methodology issues and open questions—a review from the VascAgeNet COST Action

2024-02-20Journal article Open access
Simple item page
dc.contributor.authorPUCCI, Giacomo
dc.contributor.authorGrillo, Andrea
dc.contributor.authorDALAKLEIDI, KALLIOPI
dc.contributor.authorFraenkel, Emil
dc.contributor.authorGkaliagkousi, Eugenia
dc.contributor.authorGolemati, Spyretta
dc.contributor.authorGuala, Andrea
dc.contributor.authorHametner, Bernhard
dc.contributor.authorLAZARIDIS, ANTONIOS
dc.contributor.authorMayer, Christopher
dc.contributor.authorMozos, Ioana
dc.contributor.authorPereira, Telmo
dc.contributor.authorVeerasingam, Dave
dc.contributor.authorTerentes-Printzios, Dimitrios
dc.contributor.authorAgnoletti, Davide
dc.date.accessioned2024-02-21T15:42:02Z
dc.date.available2024-02-21T15:42:02Z
dc.date.issued2024-02-20
dc.description.abstractAtrial fibrillation (AF), the most common cardiac arrhythmia, is associated with adverse CV outcomes. Vascular aging (VA), which is defined as the progressive deterioration of arterial function and structure over a lifetime, is an independent predictor of both AF development and CV events. A timing identification and treatment of early VA has therefore the potential to reduce the risk of AF incidence and related CV events. A network of scientists and clinicians from the COST Action VascAgeNet identified five clinically and methodologically relevant questions regarding the relationship between AF and VA and conducted a narrative review of the literature to find potential answers. These are: (1) Are VA biomarkers associated with AF? (2) Does early VA predict AF occurrence better than chronological aging? (3) Is early VA a risk enhancer for the occurrence of CV events in AF patients? (4) Are devices measuring VA suitable to perform subclinical AF detection? (5) Does atrial-fibrillation-related rhythm irregularity have a negative impact on the measurement of vascular age? Results showed that VA is a powerful and independent predictor of AF incidence, however, its role as risk modifier for the occurrence of CV events in patients with AF is debatable. Limited and inconclusive data exist regarding the reliability of VA measurement in the presence of rhythm irregularities associated with AF. To date, no device is equipped with tools capable of detecting AF during VA measurements. This represents a missed opportunity to effectively perform CV prevention in people at high risk. Further advances are needed to fill knowledge gaps in this field.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationPucci, G.; Grillo, A.; Dalakleidi, K.; Fraenkel, E.; Gkaliagkousi, E.; Golemati, S.; Guala, A.; Hametner, B.; Lazaridis, A.; Mayer, C.C.; et al. Atrial Fibrillation and Early Vascular Aging: Clinical Implications, Methodology Issues and Open Questions—A Review from the VascAgeNet COST Action. J. Clin. Med. 2024, 13, 1207. https:// doi.org/10.3390/jcm13051207pt_PT
dc.identifier.doihttps:// doi.org/10.3390/jcm13051207pt_PT
dc.identifier.issn2077-0383
dc.identifier.urihttp://hdl.handle.net/10400.26/49968
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/pt_PT
dc.subjectVascular agingpt_PT
dc.subjectAtrial fibrillationpt_PT
dc.subjectArteriosclerosispt_PT
dc.subjectCardiovascular diseasept_PT
dc.subjectEndothelial dysfunctionpt_PT
dc.subjectArterial stiffnesspt_PT
dc.subjectPulse wave velocitypt_PT
dc.subjectFlow mediated dilationpt_PT
dc.subjectEnvelhecimento vascularpt_PT
dc.subjectFibrilhação atrialpt_PT
dc.subjectArteriosclerosept_PT
dc.subjectDoença cardiovascularpt_PT
dc.subjectDisfunção endotelialpt_PT
dc.subjectRigidez vascularpt_PT
dc.subjectVelocidade da onda de pulsopt_PT
dc.subjectDilatação mediada por fluxopt_PT
dc.titleAtrial fibrillation and early vascular aging: clinical implications, methodology issues and open questions—a review from the VascAgeNet COST Actionpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceBaselpt_PT
oaire.citation.titleJournal of Clinical Medicinept_PT
oaire.citation.volume13pt_PT
person.familyNamePUCCI
person.familyNameGrillo
person.familyNameDALAKLEIDI
person.familyNameFraenkel
person.familyNameGkaliagkousi
person.familyNameGolemati
person.familyNameGuala
person.familyNameHametner
person.familyNameLAZARIDIS
person.familyNameMozos
person.familyNamePereira
person.familyNameVeerasingam
person.familyNameTerentes-Printzios
person.familyNameAgnoletti
person.givenNameGiacomo
person.givenNameAndrea
person.givenNameKALLIOPI
person.givenNameEmil
person.givenNameEugenia
person.givenNameSpyretta
person.givenNameAndrea
person.givenNameBernhard
person.givenNameANTONIOS
person.givenNameIoana
person.givenNameTelmo
person.givenNameDave
person.givenNameDimitrios
person.givenNameDavide
person.identifier2360906
person.identifier730202
person.identifier779139
person.identifier857269
person.identifier.ciencia-idEB19-9F1B-9811
person.identifier.orcid0000-0003-0180-859X
person.identifier.orcid0000-0002-4455-4991
person.identifier.orcid0000-0001-6702-4398
person.identifier.orcid0000-0002-3902-5067
person.identifier.orcid0000-0002-6324-2475
person.identifier.orcid0000-0003-3991-7660
person.identifier.orcid0000-0002-5006-8164
person.identifier.orcid0000-0003-2048-1019
person.identifier.orcid0000-0002-7205-4644
person.identifier.orcid0000-0001-6353-7698
person.identifier.orcid0000-0001-9119-7774
person.identifier.orcid0000-0001-6142-8180
person.identifier.orcid0000-0003-4039-8263
person.identifier.orcid0000-0001-8108-7133
person.identifier.ridK-3723-2016
person.identifier.ridM-4626-2013
person.identifier.scopus-author-id36792967600
person.identifier.scopus-author-id12764376000
person.identifier.scopus-author-id6603094406
person.identifier.scopus-author-id56416092500
person.identifier.scopus-author-id49963411500
person.identifier.scopus-author-id55817129100
person.identifier.scopus-author-id24391294200
person.identifier.scopus-author-id25652286900
person.identifier.scopus-author-id24466223600
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication1f015016-80ff-4f6a-9f72-aed90daf3406
relation.isAuthorOfPublication9363e564-7753-4149-92a6-1c6090beabed
relation.isAuthorOfPublication4d3dd465-0649-471f-bbf9-fd87c934479e
relation.isAuthorOfPublicationd71ee436-809c-4b9e-84e2-c7372487f109
relation.isAuthorOfPublicationc57ae2d8-ff63-4091-baca-4a3e98f3728b
relation.isAuthorOfPublication6a3900d3-285d-4062-9ce9-1beb055412b6
relation.isAuthorOfPublication3a8a0f0d-da67-4fdb-888c-2916d0e2c854
relation.isAuthorOfPublication090978b9-8bf9-4f8c-b925-34bbb9a9fb32
relation.isAuthorOfPublication29410876-c371-4d12-b287-880b0ee1808f
relation.isAuthorOfPublicationa3c85833-b0de-41e8-8098-fc1d82419a0a
relation.isAuthorOfPublication85969647-47cc-47ee-bec2-1360f30ae958
relation.isAuthorOfPublicationa63796f5-b10a-421a-8f5d-4d619ce4e8ba
relation.isAuthorOfPublication6ce101ff-f891-4dc0-8542-aab42e759479
relation.isAuthorOfPublication0305015b-eda6-4d51-a275-11b5d42749a6
relation.isAuthorOfPublication.latestForDiscovery85969647-47cc-47ee-bec2-1360f30ae958

Files

Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
Atrial fibrillation and early vascular aging ....pdf
Size:
616.05 KB
Format:
Adobe Portable Document Format
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.85 KB
Format:
Item-specific license agreed upon to submission
Description:
Download

Collections

IPC-ESTeSC - Artigos em revistas