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Exploring the translational challenge for medical applications of ionising radiation and corresponding radiation protection research

2022-03-18Journal article Open access
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dc.contributor.authorBockhold, Sophie
dc.contributor.authorFoley, Shane J.
dc.contributor.authorRainford, Louise A.
dc.contributor.authorCorridori, Riccardo
dc.contributor.authorEberstein, Annika
dc.contributor.authorHoeschen, Christoph
dc.contributor.authorKonijnenberg, Mark W.
dc.contributor.authorMolyneux-Hodgson, Susan
dc.contributor.authorPaulo, Graciano
dc.contributor.authorSantos, Joana
dc.contributor.authorMcNulty, Jonathan P.
dc.date.accessioned2022-04-19T15:45:39Z
dc.date.available2022-04-19T15:45:39Z
dc.date.issued2022-03-18
dc.description.abstractBackground: Medical applications of ionising radiation and associated radiation protection research often encounter long delays and inconsistent implementation when translated into clinical practice. A coordinated efort is needed to analyse the research needs for innovation transfer in radiation-based high-quality healthcare across Europe which can inform the development of an innovation transfer framework tailored for equitable implementation of radiation research at scale. Methods: Between March and September 2021 a Delphi methodology was employed to gain consensus on key translational challenges from a range of professional stakeholders. A total of three Delphi rounds were conducted using a series of electronic surveys comprised of open-ended and closed-type questions. The surveys were disseminated via the EURAMED Rocc-n-Roll consortium network and prominent medical societies in the feld. Approximately 350 professionals were invited to participate. Participants’ level of agreement with each generated statement was captured using a 6-point Likert scale. Consensus was defined as median≥4 with≥60% of responses in the upper tertile of the scale. Additionally, the stability of responses across rounds was assessed. Results: In the first Delphi round a multidisciplinary panel of 20 generated 127 unique statements. The second and third Delphi rounds recruited a broader sample of 130 individuals to rate the extent to which they agreed with each statement as a key translational challenge. A total of 60 consensus statements resulted from the iterative Delphi process of which 55 demonstrated good stability. Ten statements were identifed as high priority challenges with≥80% of statement ratings either ‘Agree’ or ‘Strongly Agree’. Conclusion: A lack of interoperability between systems, insuficient resources, unsatisfactory education and training, and the need for greater public awareness surrounding the benefts, risks, and applications of ionising radiation were identifed as principal translational challenges. These findings will help to inform a tailored innovation transfer framework for medical radiation research.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doi10.1186/s12967-022-03344-4pt_PT
dc.identifier.issn1479-5876
dc.identifier.urihttp://hdl.handle.net/10400.26/40240
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherBMCpt_PT
dc.relationEURopeAn MEDical application and Radiation prOteCtion Concept: strategic research agenda aNd ROadmap interLinking to heaLth and digitisation aspects
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/pt_PT
dc.subjectTranslational medical researchpt_PT
dc.subjectDelphi studypt_PT
dc.subjectIonising radiationpt_PT
dc.subjectRadiation protectionpt_PT
dc.subjectPesquisa médica translacionalpt_PT
dc.subjectTécnica Delphipt_PT
dc.subjectRadiação ionizantept_PT
dc.subjectProteção radiológicapt_PT
dc.titleExploring the translational challenge for medical applications of ionising radiation and corresponding radiation protection researchpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.awardTitleEURopeAn MEDical application and Radiation prOteCtion Concept: strategic research agenda aNd ROadmap interLinking to heaLth and digitisation aspects
oaire.awardURIinfo:eu-repo/grantAgreement/EC/H2020/899995/EU
oaire.citation.issue1pt_PT
oaire.citation.titleJournal of Translational Medicinept_PT
oaire.citation.volume20pt_PT
oaire.fundingStreamH2020
person.familyNameDO NASCIMENTO NOBRE PAULO
person.familyNameSantos
person.givenNameGRACIANO
person.givenNameJoana
person.identifier.ciencia-idF617-CC4E-D6CE
person.identifier.ciencia-id9D1D-1B94-9FF5
person.identifier.orcid0000-0001-6297-778X
person.identifier.orcid0000-0002-8923-5820
person.identifier.scopus-author-id56589185100
project.funder.identifierhttp://doi.org/10.13039/501100008530
project.funder.nameEuropean Commission
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublication4cb5ce05-b691-426b-ab15-ed4febf1f687
relation.isAuthorOfPublication1b92dc7a-9b94-4d80-9338-5ba67ba06991
relation.isAuthorOfPublication.latestForDiscovery4cb5ce05-b691-426b-ab15-ed4febf1f687
relation.isProjectOfPublication724f2025-d95c-4eef-bf4a-04a92561e37c
relation.isProjectOfPublication.latestForDiscovery724f2025-d95c-4eef-bf4a-04a92561e37c

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