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Oxidative stress in relation to aging and exercise

2022-08-25Journal article Open access
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dc.contributor.authorVerhaegen, Dimphna
dc.contributor.authorSmits, Kelly
dc.contributor.authorOsório, Nádia
dc.contributor.authorCaseiro, Armando
dc.date.accessioned2023-04-28T15:56:16Z
dc.date.available2023-04-28T15:56:16Z
dc.date.issued2022-08-25
dc.description.abstractDefinition: Oxidative stress is an imbalance between oxidants and antioxidants in favor of the oxidants, resulting in disruption of redox signaling and control and causing molecular damage. Oxidative stress is related to a variety of diseases, for example, cardiovascular diseases, neurodegenerative diseases, infections, and cancer. It might be that oxidative stress, and, more specifically, reactive oxygen species (ROS), affects longevity in a subtle way through signaling. Possible therapies to reduce oxidative stress in the elderly are nutritional intervention (for example, caloric restriction (CR)) and exercise. Exercise is associated with favorable changes in the expression of antioxidant enzymes and the oxidative stress status in general. A diet with CR also seems to be a promising way to reduce oxidative stress by decreasing oxidant emission and improving antioxidant mechanisms. A better understanding of where the antioxidant mechanisms in the elderly fail could be a big step forward in developing new therapies (such as exercise or diet) that prevent oxidative damage and cellular dysfunction with age.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.doihttps://doi.org/10.3390/ encyclopedia2030105pt_PT
dc.identifier.issn2673-8392
dc.identifier.urihttp://hdl.handle.net/10400.26/44676
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.publisherMDPIpt_PT
dc.rights.urihttp://creativecommons.org/licenses/by-nc-sa/4.0/pt_PT
dc.subjectOxidative stresspt_PT
dc.subjectAgingpt_PT
dc.subjectExercisept_PT
dc.subjectGlutathionept_PT
dc.subjectSuperoxide dismutasept_PT
dc.subjectReactive oxygen speciespt_PT
dc.subjectAntioxidantspt_PT
dc.subjectCortisolpt_PT
dc.subjectStress oxidativopt_PT
dc.subjectEnvelhecimentopt_PT
dc.subjectExercício físicopt_PT
dc.subjectSuperóxido dismutasept_PT
dc.subjectEspécies reativas de oxigéniopt_PT
dc.subjectAntioxidantespt_PT
dc.subjectHidrocortisonapt_PT
dc.titleOxidative stress in relation to aging and exercisept_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.conferencePlaceBasel, Switzerlandpt_PT
oaire.citation.endPage1558pt_PT
oaire.citation.startPage1545pt_PT
oaire.citation.titleEncyclopediapt_PT
oaire.citation.volume2pt_PT
person.familyNameOsório
person.familyNameCaseiro
person.givenNameNádia
person.givenNameArmando
person.identifier.ciencia-id271E-2D9B-E7F3
person.identifier.ciencia-id4012-A0D8-66D6
person.identifier.orcid0000-0001-9559-2165
person.identifier.orcid0000-0001-7844-0506
person.identifier.ridL-8385-2013
person.identifier.scopus-author-id57188973499
person.identifier.scopus-author-id35738464000
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT
relation.isAuthorOfPublicationf98c6cd7-be5f-4d66-bbf5-7ae3746e3d6b
relation.isAuthorOfPublication3736a1f3-88d6-42fb-94fc-ecd5484412de
relation.isAuthorOfPublication.latestForDiscoveryf98c6cd7-be5f-4d66-bbf5-7ae3746e3d6b

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