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Personalized medicine: paradigm shift in ALK positive non-small cell lung cancer: a case report

dc.contributor.authorBarreira, JV
dc.contributor.authorMendes, JL
dc.contributor.authorParmanande, A
dc.date.accessioned2023-09-10T20:23:28Z
dc.date.available2023-09-10T20:23:28Z
dc.date.issued2023
dc.description.abstractBackground: Since the identification of multiple therapeutic targets, as is the case of anaplastic lymphoma kinase (ALK) translocation, the paradigm of treating patients with non-small cell lung cancer (NSCLC) has improved. In order to guarantee the possibility of longer survival outcomes with a better quality of life we must invest in the determination, in suitable time, of the consensual biomarkers and in the availability of the best treatments to our patients. Case presentation: We present a case of a caucasian male in his fifth decade of life, non-smoker, who highlights the complex journey of ALK-positive patients. This particular case, demonstrates the efficacy and tolerability of the new ALK target therapies, allowing our patients to maintain their routines without compromising the effectiveness of the therapy. Conclusion: Focusing on the reality of ALK positive patients and the impact that this therapy has on the daily lives of our patients, we can contribute to the awareness of this specific pathology.pt_PT
dc.description.versioninfo:eu-repo/semantics/publishedVersionpt_PT
dc.identifier.citationJ Med Case Rep . 2023 Sep 2;17(1):374.pt_PT
dc.identifier.doi10.1186/s13256-023-04107-5pt_PT
dc.identifier.urihttp://hdl.handle.net/10400.26/46478
dc.language.isoengpt_PT
dc.peerreviewedyespt_PT
dc.subjectNeoplasias do Pulmãopt_PT
dc.subjectCarcinoma Pulmonar de Células não Pequenaspt_PT
dc.subjectLung Neoplasmspt_PT
dc.subjectCarcinoma, Non-Small-Cell Lungpt_PT
dc.titlePersonalized medicine: paradigm shift in ALK positive non-small cell lung cancer: a case reportpt_PT
dc.typejournal article
dspace.entity.typePublication
oaire.citation.issue1pt_PT
oaire.citation.titleJournal of Medical Case Reportspt_PT
oaire.citation.volume17pt_PT
rcaap.rightsopenAccesspt_PT
rcaap.typearticlept_PT

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