Browsing by Author "Santos, J."
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- Mechanical construction and installation of the ATLAS tile calorimeterPublication . ATLAS Tile Calorimeter collaboration (234 authors); Alves, R.; Amaral, P.; Carvalho, J.; David, M.; Gomes, A.; Maio, A.; Marques, C.; Onofre, A.; Pereira, A.; Pina, J.; Pinhão, J.; Santos, J.; Saraiva, J.G.; Silva, J.This paper summarises the mechanical construction andinstallation of the Tile Calorimeter for the ATLASexperiment at the Large Hadron Collider in CERN, Switzerland. The TileCalorimeter is a sampling calorimeter using scintillator as the sensitivedetector and steel as the absorber and covers the central region of the ATLASexperiment up to pseudorapidities ±1.7. The mechanical construction ofthe Tile Calorimeter occurred over a periodof about 10 years beginning in 1995 with the completionof the Technical Design Report and ending in 2006 with the installationof the final module in the ATLAS cavern. Duringthis period approximately 2600 metric tons of steel were transformedinto a laminated structure to form the absorber of the sampling calorimeter.Following instrumentation and testing, which is described elsewhere, themodules were installed in the ATLAS cavern with a remarkable accuracy fora structure of this size and weight.
- New findings in HCV genotype distribution in selected West European, Russian and Israeli regionsPublication . Kartashev, Vladimir; Döring, Matthias; Nieto, Leonardo; Coletta, Eleda; Kaiser, Rolf; Sierra, Saleta; HCV EuResist Study group; Guerrero, A.; Stoiber, H.; Paar, C.; Vandamme, A. M.; Nevens, F.; Ranst, M. Van; Cuypers, L.; Braun, P.; Ehret, R.; Obermeier, M.; Schneeweiss, S.; Scholten, S.; Römer, K.; Isernhagen, K.; Qurashi, N.; Heger, E.; Knops, E.; Neumann-Fraune, M.; Timm, J.; Walker, A.; Lübke, N.; Wedemeyer, H.; Wiesch, J. Schulze zur; Lütgehetmann, M.; Polywka, S.; Däumer, M.; Hoffmann, D.; Protzer, U.; Marascio, N.; Foca, A.; Liberto, M. C.; Barreca, G. S.; Galati, L.; Torti, C.; Pisani, V.; Perno, C. F.; Ceccherini-Silberstein, F.; Cento, V.; Ciotti, M.; Zazzi, M.; Rossetti, A.; De Luca, A.; Caudai, C.; Mor, O.; Devaux, C.; Staub, T.; Araujo, F.; Gomes, P.; Cabanas, J.; Markin, N.; Khomenko, I.; Govorukhina, M.; Lugovskaya, G.; Dontsov, D.; Mas, A.; Martró, E.; Saludes, V.; Rodríguez-Frías, F.; García, F.; Casas, P.; Iglesia, A. de la; Alados, J. C.; Pena-López, M. J.; Rodríguez, M. J.; Galán, J. C.; Suárez, A.; Cardeñoso, L.; Guerrero, M. D.; Vegas-Dominguez, C.; Blas-Espada, J.; García, R.; García-Bujalance, S.; Benítez-Gutiérrez, L.; Mendoza, C. de; Montiel, N.; Santos, J.; Viciana, I.; Delgado, A.; Martínez-Sanchez, P. A.; Fernández-Alonso, M.; Reina, G.; Trigo, M.; Echeverría, M. J.; Aguilera, A.; Navarro, D.; Bernal, S.; Lozano, M. C.; Fernández-Cuenca, F.; Orduña, A.; Eiros, J. M.; Ortíz de Lejarazu, R.; Martínez-Sapiña, A. M.; García-Díaz, A.; Haque, T.BACKGROUND: HCV affects 185 million people worldwide and leads to death and morbidities. HCV has a high genetic diversity and is classified into seven genotypes and 67 subtypes. Novel anti-HCV drugs (Direct-Acting-Antivirals) eligibility, resistance and cure rates depend on HCV geno/subtype (GT). OBJECTIVES: Analysis of epidemiological information and viral GT from patients undergoing viral genotyping in 2011-2015. STUDY DESIGN: Anonymized information from 52 centers was analyzed retrospectively. RESULTS: 37,839 samples were included in the study. We show that the GT distribution is similar throughout Western European countries, with some local differences. Here GTs 1 and 2 prevalences are lower and of GT4 higher than in all previous reports. Israel has a unique GT pattern and in South Russia the GT proportions are more similar to Asia. GTs 5 and 6 were detected in very low proportions. Three cases of the recombinant genotype P were reported in Munich (Germany). In addition, we observed that GT proportion was dependant on patientś gender, age and transmission route: GTs 1b and 2 were significantly more common in female, older, nosocomially-infected patients, while GTs 1a, 3 and 4 were more frequent in male, younger patients infected by tattooing, drug consume, and/or sexual practices. In infections acquired by drug consume, GTs 1a (35.0%) and 3 (28.1%) prevailed. In infections related to sexual practices lower proportion of GT3 (14.0%) and higher of GT4 (20.2%) were detected. GT4 was mostly abundant in MSM (29.6%). HIV coinfection was significantly associated with higher proportions GTs 1a and 4 (42.5% and 19.3%, respectively). CONCLUSION: Genotype prevalence evolves and correlates to epidemiological factors. Continuous surveillance is necessary to better assess hepatitis C infection in Europe and to take appropriate actions
- O papel da lista de verificação de segurança cirúrgica na melhoria da segurança perioperatóriaPublication . Neves, C.; Santos, D.; Rosado, F.; Santos, J.; Saramago, M.; Gomes, R.; Miranda, L.; Antunes, V.