Percorrer por autor "Nobre, Ana Rita"
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- Phonological memory in patients with head and neck tumorsPublication . Trigueiro, Natália; Pina, Flávia; Nobre, Ana Rita; Serrano, Margarida Maria Fernandes, 1964-Background, Hearing loss is one of the major complications of head and neck tumors. The combination of chemotherapy with cisplatin and radiotherapy, increased survival, becoming the standard of treatment for locally advanced tumors. However, all types of treatment, radiation therapy and chemotherapy with cisplatin, are known for their ototoxic effects. These treatments also impact the memory and brain structures associated with it. The present study aims to evaluate auditory thresholds and phonological memory changes in the individual with head and neck tumors submitted to chemotherapy and radiotherapy compared to a matched control group of age and sex who have never undergone this type of treatment, in order to alert about the hearing loss in these patients and to be created measures for the cognitive training plans in oncological patients submitted at these treatments. Material and Methods, The sample was constructed by 24 patients with head and neck tumors of the Portuguese Oncology Institute of Coimbra Francisco Gentil E. P. E. and 24 individuals without oncological disease. The tests used were: pure tone audiogram (500Hz, 1000Hz, 2000Hz, 4000Hz, 6000Hz, 8000Hz), words repetion test, pseudowords repetion test (phonological memory test), memory test and all were realized at 65dB, in silence and noise conditions. Results,The performance of the group of patients with tumor was worse in all tests. Statistical differences between groups were found in auditory thresholds, in words repetition and in pseudowords repetition test (p <0.05). Conclusion, The ototoxicity of the treatments was confirmed by the pure tone audiogram that auditory thresholds are worse in head and neck tumor patients. Regarding phonological memory, considering the result of the repetition test of words and pseudowords, it can be seen that it is impaired by chemotherapy and / or radiotherapy as a treatment of head and neck tumors. It’s essential to alert health professionals and family members about hearing loss in tumor patients, to be created measures for the evaluation and training of patient’s memory.
- Vestibular dysfunctions:comparison between patients with head and neck tumors and a control groupPublication . Nobre, Ana Rita; Silva, Carla Matos, 1975-; Guiomar, Júlia; Martins, TâniaBackground, the use of ototoxic drugs is common in patients with head and neck tumors. Consequently, there may be vestibular dysfunctions that are not always detected, affecting the quality of life. Thus, it is important to evaluate the factors that may lead to vestibular system dysfunction. The objective of this study is to determine if vestibular dysfunction in individuals with head and neck tumors who underwent chemotherapy and/or radiotherapy also occurred in a control group. Material and Methods, the sample consists of 54 individuals of both genders, aged between 20 and 91 years old and is divided into two groups: a group of 30 individuals without any kind of tumor and no medical history of chemotherapy and/or radiotherapy (control group) and a group of 24 individuals with head and neck tumors. The instruments used to collect the data were an Anamnesis, the modified Clinical Test of Sensory Interaction and Balance (mCTSIB), Limits of Stability test (LOS) and the Dizziness Handicap Inventory (DHI) scale. Results, there are statistically significant differences between the two groups on the Physical, Functional and Emotional sub-scales of the DHI scale, on the DHI Total (p DHI Physical < 0,0001; p DHI Functional < 0,0001; p DHI Emotional < 0,0001; p DHI Total < 0,0001) and on the Reaction Time (RT) in LOS test in every position (p RT Front = 0,020, p RT Back = 0,011, p RT Right = 0,036, p RT Left = 0,036). There are marginally significant differences between the two groups in the postural oscillation velocity in Condition 4 of the mCTSIB (p Condition 4 = 0,065). Conclusion, the group of individuals with head and neck tumors had worse results on the DHI scale, in the RT in LOS test and in the Condition 4 of the mCTSIB, suggesting the existence of greater vestibular alterations in this group compared to the control group.