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Percorrer por autor "Henriques, J"

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  • Global Chronic Total Occlusion Crossing Algorithm
    Publication . Wu, EB; Brilakis, ES; Mashayekhi, K; Tsuchikane, E; Alaswad, K; Araya, M; Avran, A; Azzalini, L; Babunashvili, AM; Bayani, B; Behnes, M; Bhindi, R; Boudou, N; Boukhris, M; Bozinovic, NZ; Bryniarski, L; Bufe, A; Buller, CE; Burke, MN; Buttner, A; Cardoso, P; Carlino, M; Chen, JY; Christiansen, EH; Colombo, A; Croce, K; de los Santos, FD; de Martini, T; Dens, J; di Mario, C; Dou, K; Egred, M; Elbarouni, B; ElGuindy, A; Escaned, J; Furkalo, S; Gagnor, A; Galassi, AR; Garbo, R; Gasparini, G; Ge, J; Ge, L; Goel, P; Goktekin, O; Gonzalo, N; Grancini, L; Hall, A; Hanna Quesada, F; Hanratty, C; Harb, S; Harding, S.; Hatem, R; Henriques, J; Hildick-Smith, D; Hill, J; Hoye, A; Jaber, W; Jaffer, F; Jang, Y; Jussila, R; Kalnins, A; Kalyanasundaram, A; Kandzari, D; Kao, HL; Karmpaliotis, D; Kassem, HH; Khatri, J; Knaapen, P; Kornowski, R; Krestyaninov, O; Kumar, A; Lamelas, P; Lee, SW; Lefevre, T; Leung, R; Li, Y; Li, Y; Lim, ST; Lo, S; Lombardi, W; Maran, A; McEntegart, M; Moses, J; Munawar, M; Navarro, A; Ngo, H; Nicholson, W; Oksnes, A; Olivecrona, G; Padilla, L; Patel, M; Pershad, A; Postu, M; Qian, J; Quadros, A; Rafeh, NA; Råmunddal, T; Prakasa Rao, VS; Reifart, N; Riley, RF; Rinfret, S; Saghatelyan, M; Sianos, G; Smith, E; Spaedy, A; Spratt, J; Stone, G; Strange, JW; Tammam, KO; Thompson, CA; Toma, A; Tremmel, JA; Trinidad, RS; Ungi, I; Vo, M; Vu, VH; Walsh, S; Werner, G; Wojcik, J; Wollmuth, J; Xu, B; Yamane, M; Ybarra, LF; Yeh, RW; Zhang, Q
    The authors developed a global chronic total occlusion crossing algorithm following 10 steps: 1) dual angiography; 2) careful angiographic review focusing on proximal cap morphology, occlusion segment, distal vessel quality, and collateral circulation; 3) approaching proximal cap ambiguity using intravascular ultrasound, retrograde, and move-the-cap techniques; 4) approaching poor distal vessel quality using the retrograde approach and bifurcation at the distal cap by use of a dual-lumen catheter and intravascular ultrasound; 5) feasibility of retrograde crossing through grafts and septal and epicardial collateral vessels; 6) antegrade wiring strategies; 7) retrograde approach; 8) changing strategy when failing to achieve progress; 9) considering performing an investment procedure if crossing attempts fail; and 10) stopping when reaching high radiation or contrast dose or in case of long procedural time, occurrence of a serious complication, operator and patient fatigue, or lack of expertise or equipment. This algorithm can improve outcomes and expand discussion, research, and collaboration.
    2021Artigo científico Acesso aberto Ver mais
  • A Nonrandomized, Open-Label, Multicenter, Phase 4 Pilot Study on the Effect and Safety of ILUVIEN® in Chronic Diabetic Macular Edema Patients Considered Insufficiently Responsive to Available Therapies (RESPOND)
    Publication . Figueira, J; Henriques, J; Amaro, M; Rosas, V; Alves, D; Cunha-Vaz, J
    PURPOSE: The aim of this study was to assess the effectiveness and safety of ILUVIEN® in patients with chronic diabetic macular edema (DME) who were insufficiently responsive to prior therapies. METHODS: This is a prospective, nonrandomized, multicenter, open-label, phase 4 pilot study assessing the effectiveness and safety of ILUVIEN® involving 12 patients insufficiently responsive to available therapies. Assessments were performed at screening, baseline, week 1, and months 1, 3, 6, 9, and 12. Demographics, medical/ophthalmic history, prior laser, anti-VEGF, and steroid treatments, and lab tests were recorded at screening. A complete ophthalmic examination and SD-OCT were performed at screening and at all follow-up visits. RESULTS: The patients showed improvements in best-corrected visual acuity (+3.7 letters), with greater improvement among pseudophakic patients (+6.8 letters) compared with phakic patients (-2.5 letters) 12 months after ILUVIEN®. The mean central subfield thickness decrease from baseline to month 12 was statistically significant, with a rapid reduction in the first week. Regarding safety, only 2 patients showed an intraocular pressure (IOP) increase over 25 mm Hg during the study, and the rise in IOP was well managed with eye drops only. CONCLUSIONS: This prospective and pilot study suggests that ILUVIEN® is safe and may be considered effective for chronic DME patients insufficiently responsive to other available therapies as it showed a rapid and sustained improvement of macular edema obtained after treatment with ILUVIEN®.
    2017-02-09Artigo científico Acesso aberto Ver mais