Browsing by Author "Guariza-Filho, Odilon"
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- Is there scientific evidence of the mouthwashes effectiveness in reducing viral load in Covid-19?: a systematic reviewPublication . Cavalcante-Leão, Bianca; Araujo, Cristiano; Basso, Isabela; Schroder, Angela; Guariza-Filho, Odilon; Ravazzi, Glória; Gonçalves, Flavio; Zeigelboim, Bianca; Sampaio Santos, Rosane; Neto, José StechmanBackground: The aim of this research is to verify whether there is evidence in the literature regarding the decrease in viral load present in saliva after using three types of mouthwashes. Material and Methods: Clinical and/or in vitro experimental studies that have used mouthwashes as a form of intervention to reduce the viral load in saliva were included. Combinations of words and appropriate truncations were adapted for each of the seven selected electronic bases including grey literature. Results: The selection of articles was carried out in two phases by two independent reviewers. After removing duplicate articles, 1245 references were maintained, and 2 articles were included in the Systematic Review. Both studies were performed in vitro and tested the virucidal action of the PVP-I solution for mouthwash at two different concentrations, 1% without dilution and 7% with 1:30 dilution, on the SARS-CoV and MERS-CoV viruses. Both showed a viral reduction of ≥ 99.99% with 15 s exposure. Conclusions: Based on the evidence currently available in the literature, PVP-I, at concentrations of 1 and 7%, appears to be the most effective mouthwash for reducing the viral load of COVID-19 present in human saliva. However, the guidelines for dental care refer to the use of hydrogen peroxide but there is insufficient scientific evidence to support this recommendation.
- Prevalence of orofacial pain in adults with cleft lip/palatePublication . Ravazzi, Gloria; Santos, Rosane Sampaio; Cavalcante-Leão, Bianca; Tonocchi, Rita de Cassia; Guariza-Filho, Odilon; Neto, JoséObjective: Functional disorders in individuals with cleft lip and palate (CL/P) can compromise structures of the stomatognathic system, which is one of the causes of orofacial pain in this group of patients. Numerous mechanisms of orofacial pain, particularly painful temporomandibular disorders (TMD-P), may be related to these conditions and have the potential to be the cause of diffuse. So, the objective of research wasdetermine the prevalence of orofacial pain using validated instruments on individuals with CL/P. Materials and Methods: a observational study was conducted with an intentional random sample of patients with CL/P (n = 80). Two questionnaires were administered: a screening scale for painful TMD (AAOP) and the Graded Chronic Pain Scale (GCPS). Results: In the AAOP screening questionnaire, 75% of individuals with CL / P answered affirmatively to at least one question. The most significant questions were those related to noise (p = 0.007), mandibular movement (p = 0.032) and orofacial pain region (p = 0.044) demonstrated the importance of investigating TMD-P. Regarding the impact of chronic pain in relation to activities of daily living (GCPS), although no significant, it showed that for most individuals with CL / P, it has a low disability, regardless of its intensity (low / high), being more prevalent in older individuals (p = 0.013). Conclusions: the investigation of orofacial pain should be part of the routine at services that work with CL/P patients and should be counseled to seek help for such pain, which can affect their daily living.