Loading...
Publication
Xylose metabolism in bacteria : opportunities and challenges towards efficient lignocellulosic biomass-based biorefineries
| Name: | Description: | Size: | Format: | |
|---|---|---|---|---|
| 923.89 KB | Adobe PDF |
Advisor(s)
Abstract(s)
In a sustainable society based on circular economy, the use of waste lignocellulosic biomass (LB) as feedstock for biorefineries is a promising solution, since LB is the world’s most abundant renewable and non-edible raw material. LB is available as a by-product from agricultural and forestry processes, and its main components are cellulose, hemicellulose, and lignin. Following suitable physical, enzymatic, and chemical steps, the different fractions can be processed and/or converted to value-added products such as fuels and biochemicals used in several branches of industry through the implementation of the biorefinery concept. Upon hydrolysis, the carbohydrate-rich fraction may comprise several simple sugars (e.g., glucose, xylose, arabinose, and mannose) that can then be fed to fermentation units. Unlike pentoses, glucose and other hexoses are readily processed by microorganisms. Some wild-type and genetically modified bacteria can metabolize xylose through three different main pathways of metabolism: xylose isomerase pathway, oxidoreductase pathway, and non-phosphorylative pathway (including Weimberg and Dahms pathways). Two of the commercially interesting intermediates of these pathways are xylitol and xylonic acid, which can accumulate in the medium either through manipulation of the culture conditions or through genetic modification of the bacteria. This paper provides a state-of-the art perspective regarding the current knowledge on xylose transport and metabolism in bacteria as well as envisaged strategies to further increase xylose conversion into valuable products.
Description
Keywords
D-xylose biorefinery circular economy sustainable processes xylose metabolism in bacteria
Pedagogical Context
Citation
Domingues R, Bondar M, Palolo I, Queirós O, de Almeida CD, Cesário MT. Xylose Metabolism in Bacteria—Opportunities and Challenges towards Efficient Lignocellulosic Biomass-Based Biorefineries. Applied Sciences. 2021; 11(17):8112. https://doi.org/10.3390/app11178112
Publisher
MDPI