RAS gene polymorphisms, classical risk factors and the advent of coronary artery disease in the Portuguese population

Freitas, Ana I; Mendonça, Isabel; Brión, Maria; Sequeira, Miguel M; Reis, Roberto P; Carracedo, Angel; Brehm, António

http://hdl.handle.net/10400.26/28008

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Abstract(s)

Several polymorphisms within the renin-angiotensin system cluster of genes have been associated with the advent of coronary artery disease (CAD) or related pathologies. We investigated the distribution of 5 of these polymorphisms in order to find any association with CAD development and distinguish if any of the biochemical and behavioural factors interact with genetic polymorphisms in the advent of the disease.

Keywords

Angiotensinogen Coronary Artery Disease Gene Frequency Genes, RAS Genetic Predisposition to Disease Peptidyl-Dipeptidase A Polymorphism, Genetic Portugal Risk Factors Madeira

URI

http://hdl.handle.net/10400.26/28008

Citation

Freitas, A. I., Mendonça, I., Brión, M., Sequeira, M. M., Reis, R. P., Carracedo, A., & Brehm, A. (2008). RAS gene polymorphisms, classical risk factors and the advent of coronary artery disease in the Portuguese population. BMC cardiovascular disorders, 8(1), 15.