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- In vitro comparative study of microhardness and flexural strength of acrylic resins used in removable denturesPublication . Costa, Marta; Neves, Sara; Carvalho, Joana; Arantes-Oliveira, Sofia; Félix, SérgioPolymethylmethacrylate is the material of choice for prosthetic bases. Depending on the type of polymerization, acrylic resins may present some mechanical weaknesses that may lead to the failure of a prosthesis. The microhardness and flexural strength of a dental material determine its applicability. The objective of the present investigation was to evaluate the in vitro Knoop microhardness and flexural strength of a thermopolymerizable (Probase Hot) and an autopolymerizable (Probase Cold) resin, according to ISO 20759-1: 2013.