Browsing by Author "Valadas, E."
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- Pharmacogenetic: screening relevant polymorphisms on antiretroviral therapy in a HIV Portuguese populationPublication . Fernandes, A.; Cruz, J. P.; Paixão, P.; Valadas, E.; Morais, J. G.; Ribeiro, A. C."Several factors cause heterogeneity of response to antiretroviral therapy. Genetic polymorphisms, particularly in metabolizing enzyme, cytochrome P450 isoenzymes and transport proteins MDR, MRP and SLC, may cause pharmacokinetic variability in some ARVs, leading to viral failure, drug toxicity and may explain the interpatient variability for drug absorption pathways."
- Searching for the G516T Polymorphism on the CYP2B6 gene in HIV-1PatientsPublication . Fernandes, A.; Aniceto, N.; Cruz, J. P.; Paixão, P.; Valadas, E.; Morais, J. G.; Ribeiro, A. C.