Browsing by Author "Brito, C"
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- Alopécia Areata: Análise Retrospectiva da Consulta de Dermatologia. Pediátrica (2000-2008)Publication . Rocha, J; Ventura, F; Vieira, AP; Pinheiro, AR; Fernandes, F; Brito, CINTRODUCTION: Alopecia areata usually presents as patchy, nonscarring hair loss. It seems to be an immune mediated disease, whereas genetic predisposition, environmental and psychological triggers may be involved in its aetiology. OBJECTIVES: To study the epidemiology, clinical aspects, associations, and treatment of alopecia areata in the paediatric population of Peadiatric Dermatology outpatients over a 9-year period. Some psychologic characteristics were also assessed. METHODS: Descriptive and retrospective study of all newly diagnosed AA cases seen from January 2000 to December 2008 at the Hospital de São Marcos' Paediatric Dermatology Department. Fifteen patients with AA were interviewed for psycologic evaluation. RESULTS: Forty-eight cases (54% male/46% female) were identified. Mean age at presentation was 7.8 years. Family history of AA was reported in 10% of the cases, and in 25% there was a personal and/or family history of atopy. The majority of patients (82%) had mild disease and topical corticotherapy was the first-line treatment for limited AA. Fifty-four percent of these patients had a complete resolution of the lesions with treatment. Systemic treatment (corticosteroids and/or ciclosporin) was used in 71% of patients with extensive disease (more than 50% hair loss). Only one of these patients had a sustained clinical improvement after treatment. Twelve out of 15 respondents (80%) recalled stressful events preceding hair loss. DISCUSSION: Our findings are similar to those reported in other studies. Epidemiologic studies of AA are available in adulthood but there is a paucity of literature on children with AA. A holistic approach is important in the management of childhood AA as the disease can have a severe psychologic impact on an individual's well-being.
- Association of adult mastocytosis with M541L in the transmembrane domain of KITPublication . Rocha, J; Duarte, ML; Marques, H; Torres, F; Tavares, P; Silva, A; Brito, C
- Bleomycin-induced flagellate hyperpigmentationPublication . Resende, C; Araújo, C; Gomes, J; Brito, CBleomycin is a chemotherapeutic agent used in the treatment of different tumours. It has several side effects, including flagellate hyperpigmentation, which is a unique and a well-documented side effect of bleomycin therapy. We report a case of a 23-year-old woman with a personal history of ovarian dysgerminoma, who developed flagellate hyperpigmentation on trunk after bleomycin therapy.
- Colloid milium successfully treated with MAL-PDTPublication . Gomes, J; Ventura, F; Duarte, ML; Brito, C
- Coma BlistersPublication . Rocha, J; Pereira, T; Ventura, F; Pardal, F; Brito, CComa blisters are lesions that occur in the setting of a variety of neurological diseases. Although most commonly associated with barbiturate overdose, they can be seen in the setting of coma due to other etiologies. Blisters develop 48-72 h after the onset of unconsciousness. We report the case of a 29-year-old man who presented to the emergency department with confusion and progressive loss of consciousness. He had high serum glucose, abnormal hepatic and kidney function tests and a normal toxicological screening. 24 h after admission he was comatose and was started on antibiotics for presumed bacterial meningoencephalitis. Two days after the onset of coma, multiple tense hemorrhagic blisters appeared on the patient's extremities. Skin biopsy revealed an intraepidermal blister with variable degrees of epidermal necrosis. Five days later the patient was fully recovered with no neurological sequelae. No topical treatment was necessary, with complete resolution of the skin lesions two weeks later.
- Conjuntivite Neonatal a Citrobacter FreudiiPublication . Lucas, M; Marques, S; Marçal, J; Rodrigues, A; Brito, C; Carvalhosa, G; Neto, AS
- Contact dermatitis due to Centella asiaticaPublication . Gomes, J; Pereira, T; Vilarinho, C; Duarte, ML; Brito, C
- Cutaneous Phaeohyphomycosis Caused by Alternaria alternata Unresponsive to Itraconazole TreatmentPublication . Gomes, J; Vilarinho, C; Duarte, ML; Brito, CCutaneous alternariosis is an opportunistic infection that has been described mainly in patients treated with corticosteroids. We report a case of dermal alternariosis occurring in a woman treated with corticosteroids after a neurosurgery that was unresponsive to itraconazole. Treatment with intravenous voriconazole was initiated, followed by oral protocol, with marked improvement of the lesions.
- Cutaneous polyarteritis nodosa in a child following hepatitis B vaccinationPublication . Ventura, F; Antunes, H; Brito, C; Pardal, F; Pereira, T; Vieira, AP
- Cutis marmorata telangiectatica congenitalPublication . Resende, CI; Araújo, C; Vieira, AP; Brito, C
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