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- ReSurveyEurope : a database of resurveyed vegetation plots in EuropePublication . Knollová, Ilona; Chytrý, Milan; Bruelheide, Helge; Dullinger, Stefan; Jandt, Ute; Bernhardt-Römermann, Markus; Biurrun, Idoia; Bello, Francesco de; Glaser, Michael; Hennekens, Stephan; Jansen, Florian; Jiménez-Alfaro, Borja; Kadaš, Daniel; Kaplan, Ekin; Klinkovská, Klára; Lenzner, Bernd; Pauli, Harald; Sperandii, Marta Gaia; Verheyen, Kris; Winkler, Manuela; Abdaladze, Otar; Aćić, Svetlana; Acosta, Alicia T. R.; Alignier, Audrey; Andrews, Christopher; Arlettaz, Raphaël; Attorre, Fabio; Axmanová, Irena; Babbi, Manuel; Baeten, Lander; Baran, Jakub; Barni, Elena; Benito-Alonso, José-Luis; Berg, Christian; Bergamini, Ariel; Berki, Imre; Boch, Steffen; Bock, Barbara; Bode, Frank; Bonari, Gianmaria; Boublík, Karel; Britton, Andrea J.; Brunet, Jörg; Bruzzaniti, Vanessa; Buholzer, Serge; Burrascano, Sabina; Campos, Juan A.; Carlsson, Bengt-Göran; Carranza, Maria Laura; Černý, Tomáš; Charmillot, Kévin; Chiarucci, Alessandro; Choler, Philippe; Chytrý, Kryštof; Corcket, Emmanuel; Csecserits, Anikó; Cutini, Maurizio; Czarniecka-Wiera, Marta; Danihelka, Jiří; Francesco, Maria Carla de; Frenne, Pieter De; Musciano, Michele Di; Sanctis, Michele De; Deák, Balázs; Decocq, Guillaume; Dembicz, Iwona; Dengler, Jürgen; Cecco, Valter Di; Dick, Jan; Diekmann, Martin; Dierschke, Hartmut; Dirnböck, Thomas; Doerfler, Inken; Doležal, Jiří; Döring, Ute; Durak, Tomasz; Dwyer, Ciara; Ejrnæs, Rasmus; Ermakova, Inna; Erschbamer, Brigitta; Fanelli, Giuliano; Fernández-Calzado, María-Rosa; Fickert, Thomas; Fischer, Andrea; Fischer, Markus; Foremnik, Kacper; Frouz, Jan; García-González, Ricardo; García-Magro, Daniel; García-Mijangos, Itziar; Gavilán, Rosario G.; Germ, Mateja; Ghosn, Dany; Gigauri, Khatuna; Gizela, Jaroslav; Golob, Aleksandra; Golub, Valentin; Gómez-García, Daniel; Gowing, David; Grytnes, John-Arvid; Güler, Behlül; Gutiérrez-Girón, Alba; Haase, Peter; Haider, Sylvia; Hájek, Michal; Halassy, Melinda; Harásek, Martin; Härdtle, Werner; Heinken, Thilo; Hester, Alison; Humbert, Jean-Yves; Ibáñez, Ricardo; Illa, Estela; Jaroszewicz, Bogdan; Jensen, Kai; Jentsch, Anke; Jiroušek, Martin; Kalníková, Veronika; Kanka, Róbert; Kapfer, Jutta; Kazakis, George; Kermavnar, Janez; Kesting, Stefan; Khanina, Larisa; Kindermann, Elisabeth; Kotrík, Marek; Koutecký, Tomáš; Kozub, Łukasz; Kuhn, Gisbert; Kutnar, Lado; Montagna, Dario La; Lamprecht, Andrea; Lenoir, Jonathan; Lepš, Jan; Leuschner, Christoph; Lorite, Juan; Madsen, Bjarke; Ugarte, Rosina Magaña; Malicki, Marek; Maliniemi, Tuija; Máliš, František; Maringer, Alexander; Marrs, Robert; Matesanz, Silvia; Metze, Katrin; Meyer, Stefan; Millett, Jonathan; Mitchell, Ruth J.; Moeslund, Jesper Erenskjold; Moiseev, Pavel; Cella, Umberto Morra di; Mudrák, Ondřej; Müller, Frank; Müller, Norbert; Naaf, Tobias; Nagy, Laszlo; Napoleone, Francesca; Nascimbene, Juri; Navrátilová, Jana; Ninot, Josep M.; Niu, Yujie; Normand, Signe; Ogaya, Romá; Onipchenko, Vladimir; Orczewska, Anna; Ortmann-Ajkai, Adrienne; Pakeman, Robin J.; Pardo, Iker; Pätsch, Ricarda; Peet, Robert K.; Penuelas, Josep; Peppler-Lisbach, Cord; Pérez-Hernández, Javier; Pérez-Haase, Aaron; Petraglia, Alessandro; Petřík, Petr; Pielech, Remigiusz; Piórkowski, Hubert; Pladevall-Izard, Eulàlia; Poschlod, Peter; Prach, Karel; Praleskouskaya, Safiya; Prokhorov, Vadim; Provoost, Sam; Pușcaș, Mihai; Pustková, Štěpánka; Randin, Christophe François; Rašomavičius, Valerijus; Reczyńska, Kamila; Rédei, Tamás; Řehounková, Klára; Richner, Nina; Risch, Anita C.; Rixen, Christian; Rosbakh, Sergey; Roscher, Christiane; Rosenthal, Gert; Rossi, Graziano; Rötzer, Harald; Roux, Camille; Rumpf, Sabine B.; Ruprecht, Eszter; Rūsiņa, Solvita; Sanz-Zubizarreta, Irati; Schindler, Meret; Schmidt, Wolfgang; Schories, Dirk; Schrautzer, Joachim; Schubert, Hendrik; Schuetz, Martin; Schwabe, Angelika; Schwaiger, Helena; Schwartze, Peter; Šebesta, Jan; Seiler, Hallie; Šilc, Urban; Silva, Vasco; Šmilauer, Petr; Šmilauerová, Marie; Sperle, Thomas; Stachurska-Swakoń, Alina; Stanik, Nils; Stanisci, Angela; Steffen, Kristina; Storm, Christian; Stroh, Hans Georg; Sugorkina, Nadezhda; Świerkosz, Krzysztof; Świerszcz, Sebastian; Szymura, Magdalena; Teleki, Balázs; Thébaud, Gilles; Theurillat, Jean-Paul; Tichý, Lubomír; Treier, Urs A.; Turtureanu, Pavel Dan; Ujházy, Karol; Ujházyová, Mariana; Ursu, Tudor Mihai; Uziębło, Aldona K.; Valkó, Orsolya; Calster, Hans Van; Meerbeek, Koenraad Van; Vandevoorde, Bart; Vandvik, Vigdis; Varricchione, Marco; Vassilev, Kiril; Villar, Luis; Virtanen, Risto; Vittoz, Pascal; Voigt, Winfried; Hessberg, Andreas von; Oheimb, Goddert von; Wagner, Eva; Walther, Gian-Reto; Wellstein, Camilla; Wesche, Karsten; Wilhelm, Markus; Willner, Wolfgang; Wipf, Sonja; Wittig, Burghard; Wohlgemuth, Thomas; Woodcock, Ben A.; Wulf, Monika; Essl, FranzAims: We introduce ReSurveyEurope — a new data source of resurveyed vegetation plots in Europe, compiled by a collaborative network of vegetation scientists. We describe the scope of this initiative, provide an overview of currently available data, governance, data contribution rules, and accessibility. In addition, we outline further steps, including potential research questions. Results: ReSurveyEurope includes resurveyed vegetation plots from all habitats. Version 1.0 of ReSurveyEurope contains 283,135 observations (i.e., individual surveys of each plot) from 79,190 plots sampled in 449 independent resurvey projects. Of these, 62,139 (78%) are permanent plots, that is, marked in situ, or located with GPS, which allow for high spatial accuracy in resurvey. The remaining 17,051 (22%) plots are from studies in which plots from the initial survey could not be exactly relocated. Four data sets, which together account for 28,470 (36%) plots, provide only presence/absence information on plant species, while the remaining 50,720 (64%) plots contain abundance information (e.g., percentage cover or cover–abundance classes such as variants of the Braun-Blanquet scale). The oldest plots were sampled in 1911 in the Swiss Alps, while most plots were sampled between 1950 and 2020. Conclusions: ReSurveyEurope is a new resource to address a wide range of research questions on fine-scale changes in European vegetation. The initiative is devoted to an inclusive and transparent governance and data usage approach, based on slightly adapted rules of the well-established European Vegetation Archive (EVA). ReSurveyEurope data are ready for use, and proposals for analyses of the data set can be submitted at any time to the coordinators. Still, further data contributions are highly welcome.
- Resilience and hopelessness mediate the relationship between benevolent childhood experiences and life satisfaction : evidence from a cross-cultural studyPublication . Sever, Melih; Tatlıcıoğlu, Oktay; Almeida, Telma Catarina; Azeez, E. P. Abdul; Caridade, Sónia; Cunha, OlgaBackground: A growing body of literature focuses on the role of benevolent childhood experiences (BCEs) in predicting adulthood well-being, in addition to adverse childhood experiences (ACEs). However, cross-cultural differences are generally ignored in this endeavor. Hence, this study aimed to explore the role of BCEs in predicting life satisfaction, resilience, and hopelessness. We also examined the potential of resilience and the role of hopelessness in mediating the relationship between BCE and life satisfaction. Methods: A total of 850 university students from Turkey (n = 371), Portugal (n = 248), and India (n = 231), aged 17 to 58 years (M = 22.12, SD = 4.41), participated in the study. Participants completed an online protocol consisting of measures to assess BCEs, life satisfaction, resilience, and hopelessness. Results: BCEs, hopelessness, and life satisfaction have significantly differed among the samples based on the country of residence. BCEs were positively correlated to resilience and life satisfaction and negatively to hopelessness. In the sequential mediation model, after controlling for country and sex, resilience and hopelessness sequentially mediated the relationship between BCEs and life satisfaction. BCEs were associated with life satisfaction, resilience, and hopelessness across countries and sexes. The model explains 42.8% of the variability. Conclusion: Despite differences between countries, BCEs are important predictors of adult well-being in all three countries and should be monitored along with ACE. Further, resilience seems to have an important role in lowering the negative consequences of lower BCEs and feelings of hopelessness, pointing to the need to strengthen psychological resilience among adults.
- Research skills developed in post-graduation and their translation into clinical nursing practicesPublication . Ferreira, Rogério; Mestre, Teresa Dionísio; Fernandes, Júlio Belo; Sousa, Luís; José, Helena; Fonseca, César; Ferreira, Óscar; Baixinho, Cristina LavaredaObjective: To explore how the development of research skills through postgraduate training is transferred to the use of research in clinical nursing practice. Method: This was a qualitative, exploratory, descriptive study developed based on a focus group in October 2021, using an intentional sample of eight postgraduate nurses from a healthcare institution in the region of Baixo Alentejo, Portugal. Bardin's content analysis was performed to analyze data. The participants and two reviewers legitimized the findings. In addition, the consolidated criteria for reporting qualitative research checklist were applied to this study to ensure the quality of the research report. Results: From the data analysis, three categories emerged: 1) transfer of research skills to clinical practice, 2) constraints to the development of research, and 3) expectations concerning the development of nursing research. Conclusion: Appreciation of research skills in contexts of practice, team involvement, improvement of nursing care outcomes, greater understanding of the research process, communication of results, and transferring knowledge to the clinic are contributions of research skills acquired in postgraduation training. The findings from this study can contribute to the development of health and nursing education policies.
- Reply to Grant, W.B. comment on “Vicente, F.; Pereira, P.C. Pork meat composition and health : a review of the evidence. Foods 2024, 13, 1905”Publication . Vicente, Filipa; Pereira, Paula C.
- Reliability and validity of the global physical activity questionnaire for Portuguese adultsPublication . Ribeiro, Mariana; Fernandes, Elisabete; Borges, Mariana; Pires, Madalena; Melo, Xavier; Pinto, Fausto J.; Abreu, Ana; Pinto, RitaThe Global Physical Activity Questionnaire (GPAQ) has been used often to assess physical activity (PA) patterns. However, the European Portuguese version of this instrument has not been validated. We aimed to validate the self-administered GPAQ, version 2, (GPAQv2) for Portuguese adults. We included 32 participants in a pilot study of a Portuguese adaptation of the test and 108 participants in an assessment of their PA patterns and sedentary behavior (SB) through the GPAQv2. For its validation, we compared the GPAQv2 to the International PA Questionnaire-Long Form (IPAQ-LF) (concurrent validity) and the ActiGraph wGT3X-BT accelerometer (criterion validity). We evaluated PA and SB at baseline and after seven consecutive days. Test-retest reliability with the Kappa test (k) and the Intraclass Correlation Coefficient (ICC) ranged from strong to almost perfect (k: 0.864–0.976) and from moderate to excellent (ICC: 0.56–0.994), respectively. Concurrent validity, assessed by Spearman’s Correlation Coefficient, was moderate to substantial (rho: 0.471–0.680), and there was fair to substantial criterion validity (rho: 0.226–0.672). Bland-Altman plots showed that the GPAQv2 overestimated vigorous and moderate to vigorous PA and underestimated moderate PA. The largest difference values were related to SB, since the GPAQv2 underestimated sitting time. In sum, we found the GPAQv2 to have acceptable validity and reliability for assessing PA and SB patterns, and we recommend its use for Portuguese adults.
- Regenerating alveolar bone for implant placement : the efficacy of autogenous mineralized dentin matrix - a systematic review and meta-analysisPublication . Meném, Madalena; Santos, Alexandre; Mascarenhas, PauloThe preservation of the alveolar ridge has gained increasing importance for various types of rehabilitation, including dental implant placement. Consequently, researchers have explored different bone grafts, such as mineralized dentin matrix grafts. However, a comprehensive review of the efficacy of autogenous mineralized dentin (AMD) for alveolar ridge preservation remains lacking. In this review, we evaluated the efficacy of AMD as a method for alveolar ridge preservation in cases of delayed implant placement. A comprehensive search through PubMed, Google Scholar, Cochrane Library, and B-on repositories was conducted without time constraints up to July 2024 to identify peer-reviewed human studies. These studies assessed the percentage of newly formed bone and residual graft following bone regeneration with AMD grafts after tooth extraction, specifically in the context of delayed implant placement. Our analysis included four selected studies involving 55 patients and 67 sockets. The findings suggest that AMD grafts resulted in an average (and 95% confidence interval) of 43.8% [36.6%, 50.8%] newly formed bone, and delayed implant placement was a feasible surgical option for all patients. Although the available literature is scarce, AMD grafting has yielded promising outcomes as a method for bone reconstruction. Nevertheless, additional randomized controlled trials with larger sample sizes and longer follow-ups are required to substantiate these findings.
- Real-world effectiveness of aromatase inhibitors and fulvestrant in HR+/HER2- advanced breast cancer : a snapshot of the last two years before conventional use of CDK 4/6 inhibitors in a Portuguese institutionPublication . Teodoro, Maria Inês; Mayer, Alexandra; Miranda, Ana da Costa; Nunes, Hugo; Costa, Filipa Alves da; Lourenço, AntónioBackground: Monotherapy with aromatase inhibitors and fulvestrant were the standard-of-care for hormone receptor-positive (HR+)/human epidermal growth factor receptor-type2 negative (HER2-) advanced breast cancer, before integration of cyclin-dependent kinase 4/6 inhibitors. Effectiveness data is essential for regulatory action, but little is known about real-world use of aromatase inhibitors and fulvestrant. Methods: A retrospective cohort study was conducted resorting to data from a cancer registry to identify adult women with HR+/HER2- advanced breast cancer exposed to aromatase inhibitors or fulvestrant (31 May 2017–31 March 2019) at the main oncology hospital in Portugal. Cases were updated with follow-up until death or cut-off (31 March 2021) and pseudoanonymized data extracted. Primary outcome was overall survival (OS) and secondary time to treatment failure (TTF), estimated using survival analysis and compared with published trials. Results: 192 patients were distributed by subgroups according to the medicine. Letrozole: OS 30.8 (95% confidence interval (CI) 20.6–41.4); TTF 11.2 (95%CI 8.7–13.7). Exemestane: OS 22.1 (95%CI 9.7–34.6); TTF 6.0 (95%CI 4.1–7.8). Fulvestrant: OS 21.6 (95%CI 16.5–26.7); TTF 5.6 (95%CI 4.5–6.6). Conclusions: Estimated effectiveness (OS) of letrozole and fulvestrant was, respectively, 3.2–3.5 months lower than reported. The clinical meaning seems uncertain and may be explained by a higher proportion of worse prognostic characteristics in patients treated in the real-world.
- Prolonged fasting induces histological and ultrastructural changes in the intestinal mucosa that may reduce absorption and revert after enteral refeedingPublication . Nunes, Gonçalo; Guimarães, Marta; Coelho, Hélder; Carregosa, Ricardo; Oliveira, Cátia; Pereira, Sofia S.; Matos, António Alves de; Fonseca, JorgeBackground: Malnutrition is usual in patients referred for endoscopic gastrostomy (PEG). Refeeding syndrome is rarely observed in PEG-fed patients, which could possibly be associated with reduced absorption induced by prolonged starvation. Objective: In patients submitted to PEG after a significant period of fasting, the present study aims to: 1. evaluate the histological/ultrastructural initial changes in the intestinal mucosa, potentially associated with reduced absorption, and 2. assess if these changes could reverse with enteral refeeding. Methods: The present study is an observational, prospective, controlled study. Adult patients with ingestion below 50% of daily needs for at least one month and/or diagnosis of malnutrition were enrolled. Duodenal biopsies were taken at baseline and after 3–6 months of PEG feeding, which then underwent histological/ultrastructural analysis. Random healthy individuals were used as controls. Results: A total of 30 patients (16 men/14 women) aged 67.1 ± 13.5 years were included. Malnutrition was found in 40% of patients. Approximately 14 patients completed follow-up during both periods (46.7%). At baseline: duodenal mucosal atrophy was evident in three patients (10%); the median villi length (MVL) was 0.4 mm (0.25–0.6 mm), with it being shorter than the controls, which was 0.6 mm (0.4–0.7 mm) (p = 0.006); ultrastructural changes included focal shortening, bending, and disruption of enterocyte microvilli, the presence of citoplasmatic autophagic vacuoles, dilation and vesiculation of the smooth endoplasmic reticulum, and the presence of dilated intercellular spaces with basement membrane detachment. After refeeding, most patients displayed normal histology (92.9%) and increase MVL (p < 0.001), ultrastructural changes disappeared, and enterocytes resumed a normal appearance, although retaining scarce, small, dense bodies in apical regions from the evolution of previous autophagy. Conclusions: Prolonged fasting induces histological and ultrastructural changes in the intestinal mucosa that may reflect impaired absorption in the early post-PEG period. These changes were reverted after refeeding with enteral nutrition.
- Prevalence and impact of revenge pornography on a sample of Portuguese womenPublication . Murça, Ana; Cunha, Olga; Almeida, Telma CatarinaVictims of revenge pornography (RP) suffer long-term psychological, personal, and social consequences, given that the spread of explicit content may continue to disturb them throughout their lives. However, there is a scarcity of studies on this phenomenon in Portugal. The present study aims to identify the prevalence of RP and analyze its impact on self-esteem, humiliation, depression, and anxiety, and compare victims and non-victims of RP on these same variables. The sample comprises 274 Portuguese women aged between 18 and 82. The data was collected through an online protocol consisting of a sociodemographic questionnaire, the Rosenberg Self-Esteem Scale, the Humiliation Inventory, and the Brief Symptoms Inventory. From the total sample, 45 (16.4%) participants reported at least one experience of RP. RP victims reported higher levels of humiliation, anxiety, and depression and lower levels of self-esteem than non-victims. However, only humiliation distinguished RP victims and non-victims. RP is a growing phenomenon enhanced by the intensified use of technology. Along with this phenomenon comes the impact on victims, which has long-term consequences. This study contributes to the scientific community since the scientific study of RP and its impact on victims is still incipient.
- Post-acute exercise cardiovagal modulation in older male adults with and without type 2 diabetesPublication . Marôco, João Luís; Arrais, Inês; Silvestre, Tiago; Pinto, Marco; Laranjo, Sérgio; Magalhães, João; Santa-Clara, Helena; Fernhall, Bo; Melo, XavierPurpose: We examined heart rate variability (HRV) and baroreflex sensitivity (BRS) disease- and age-related response at 10-and 60-min after an acute high-intensity interval (HIIE) and moderate continuous exercise (MICE) in older adults with and without type 2 diabetes mellitus (T2DM) and healthy young adults. Methods: Twelve older male adults with (57–84 years) and without T2DM (57–76 years) and 12 healthy young male adults (20–40 years) completed an isocaloric acute bout of HIIE, MICE, and a non-exercise condition in a randomized order. Time and Wavelets-derived frequency domain indices of HRV and BRS were obtained in a supine position and offline over 2-min time-bins using Matlab. Results: HIIE but not MICE reduced natural logarithm root mean square of successive differences (Ln-RMSSD) (d = − 0.85; 95% CI − 1.15 to − 0.55 ms, p < 0.001), Ln-high-frequency power (d = − 1.60; 95% CI − 2.24 to − 0.97 ms2; p < 0.001), and BRS (d = − 6.32; 95% CI − 9.35 to − 3.29 ms/mmHg, p < 0.001) in adults without T2DM (averaged over young and older adults without T2DM), returning to baseline 60 min into recovery. These indices remained unchanged in older adults with T2DM after HIIE and MICE. Older adults with T2DM had lower resting Ln-RMSSD and BRS than aged-matched controls (Ln-RMSSD, d = − 0.71, 95% CI − 1.16 to − 0.262 ms, p = 0.001; BRS d = − 3.83 ms/mmHg), 95% CI − 6.90 to − 0.76, p = 0.01). Conclusions: Cardiovagal modulation following acute aerobic exercise is intensity-dependent only in adults without T2DM, and appears age-independent. These findings provide evidence of cardiac autonomic impairments in older adults with T2DM at rest and following aerobic exercise.