CMS collaboration (2301 authors)Nayak, ArunaAraujo, MarianaBargassa, PedrameBeirão Da Cruz E Silva, CristóvãoDi Francesco, AgostinoFaccioli, PietroGalinhas, BrunoGallinaro, MicheleHollar, JonathanLeonardo, NunoSeixas, JoaoStrong, GilesToldaiev, OleksiiVadruccio, DanieleVarela, JoaoVischia, PietroDavid Tinoco Mendes, AndreSilva, PedroMusella, Pasquale2019-02-052019-02-052018-06-05http://dx.doi.org/10.1103/PhysRevLett.120.231801http://hdl.handle.net/10400.26/27613The observation of Higgs boson production in association with a top quark-antiquark pair is reported, based on a combined analysis of proton-proton collision data at center-of-mass energies of s=7, 8, and 13 TeV, corresponding to integrated luminosities of up to 5.1, 19.7, and 35.9  fb-1, respectively. The data were collected with the CMS detector at the CERN LHC. The results of statistically independent searches for Higgs bosons produced in conjunction with a top quark-antiquark pair and decaying to pairs of W bosons, Z bosons, photons, τ leptons, or bottom quark jets are combined to maximize sensitivity. An excess of events is observed, with a significance of 5.2 standard deviations, over the expectation from the background-only hypothesis. The corresponding expected significance from the standard model for a Higgs boson mass of 125.09 GeV is 4.2 standard deviations. The combined best fit signal strength normalized to the standard model prediction is 1.26-0.26+0.31.engjournal article2019-02-05