Jacinto, JoanaMalheiro, AlexandraPestana, AndreiaFreitas, TiagoBrazão, M. Luz2020-11-302020-11-302014Jacinto, Joana; Malheiro, Alexandra; Pestana, Andreia; Freitas, Tiago; Brazão, M. Luz (2014) Multiple Myeloma Presenting with Distal Limb Gangrene: An Odd Case Report.European Journal of Case Reports in Internal Medicine, 1 (1).pp. 1-5.2284-2594http://hdl.handle.net/10400.26/34182Multiple myeloma (MM) is a plasmocytic malignant proliferation of a single clone resulting in an overabundance of monoclonal immunoglobulins. MM commonly presents with bone disorders, renal failure, anaemia and hypercalcaemia. Hyperviscosity syndrome is rare, as are vaso-occlusive symptoms. The authors report a dramatic case of an 80-year-old woman admitted to the emergency department with full-blown distal gangrene. The culprit turned out to be a MM, unusually presenting with symptomatic hyperviscosity and peripheral occlusive ischaemia. This catastrophic and particularly dramatic presentation is almost unprecedented, with only a few cases reported worldwide.engmultiple myeloma (MM)dystal limb gangreneMadeira IslandPortugalplasmocytic malignant proliferationsymptomatic hyperviscosityperipheral occlusive ischaemiajournal article10.12890/2014_000167