Fernandes, SóniaBatista, ÂngeloOssmane, ElisSantos, HortenseCarvalho, LuísaMares, PedroAlves, Rui2025-12-022025-12-022025-11http://hdl.handle.net/10400.26/60154Trabalho apresentado em TMS Algarve 2025, 12-15 novembro 2025, Olhão, PortugalThis study explores stakeholder perceptions of the role of Higher Education Institutions (HEIs) in fostering entrepreneurship, knowledge transfer, and regional collaboration in two distinct European regions: Setubal (Portugal) and Vidzeme (Latvia). Using a quantitative, descriptive, and comparative methodology, data was collected through a structured questionnaire targeting academic and regional stakeholders. The analysis focused on two key dimensions: the relationship between HEIs and regional actors, and the relevance of international networks and cross-border cooperation. The results highlight a generally positive perception of HEIs’ third mission, their contribution to entrepreneurship, and their engagement in knowledge and technology transfer. Stakeholders particularly valued the role of international collaboration in promoting innovation, mobility, and economic competitiveness. Differences between regions suggest varying levels of institutional maturity and strategic alignment. The findings reinforce the importance of stakeholder engagement in higher education and provide valuable insights for enhancing HEIs’ regional impact.engHigher Education InstitutionsStakeholdersEntrepreneurshipKnowledge TransferRegional Developmentconference object