Sequeira, CarlosAraújo, OdeteLourenço, TâniaFreitas, OtíliaCarvalho, José CarlosCosta, Patrício2022-10-142022-10-142022Sequeira, C., Araújo, O., Lourenço, T., Freitas, O., Carvalho, J.C. and Costa, P. (2022), The impact of the COVID-19 pandemic on the mental health of Portuguese university students. Int J Mental Health Nurs, 31: 920-932.http://hdl.handle.net/10400.26/41927Worldwide, the COVID-19 pandemic has had a disruptive effect on daily routines, especially for university students. This study aimed to compare pre-pandemic domains of students’ mental health during the pandemic lockdown. One cross-sectional study was conducted in two waves with academic students from 20 Portuguese universities, in March 2020 before the COVID19 pandemic (n = 3579) and 2 months after the first lockdown in May 2020 (n = 1228). The Positive Mental Health Questionnaire (PMHQ), the Mental Health Knowledge Questionnaire, the Mental Health-promoting knowledge, and the Psychological Vulnerability Scale were used. Statistical analyses were performed by bivariate associations and multiple linear regression models. Students were mostly women (79%), with an average age of 23.2 years (SD = 6.6), displaced from their family environment (43%), out-of-home (43%), and scholarship holders (37%). Higher scores found in the PVS were associated with decreased PMHQ in both moments (P < 0.01). These crosssectional studies showed a slight variation in the mental health variables studied in the period before and during the COVID-19 outbreak. Being a woman, younger, out-of-home, and having a scholarship (P < 0.01) seem to increase susceptibility to mental health variation before and during the pandemic. Universities should develop strategies that promote students’ mental health.engCOVID-19LiteracyPositive mental healthUniversity studentsjournal article10.1111/inm.129991447-0349