Moranguinho, InêsBorrego, PedroGonçalves, FátimaGomes, PerpétuaRocha, JoséBarreto, JorgeTaveira, Nuno2019-12-132021-12-312019-11AIDS: November 14, 2019 - Volume Publish Ahead of Print. doi: 10.1097/QAD.00000000000024310269-93701473-5571http://hdl.handle.net/10400.26/30476The pol gene from HIV-2 infected patients from Cape Verde experiencing virologic failure was sequenced and drug resistance mutations were determined. Most patients were taking a first line regimen of AZT, 3TC and LPV/r. Resistance mutations were found in most patients (11/17, 64.7%) especially I82F (4/7, 57.1%) and M184 V (10/17, 58.8%). Resistance to all reverse transcriptase and protease inhibitors was found in 58.8% (10/17) of the patients. Integrase inhibitors are warranted to treat these patients.engHIV-2 infected patientsGenotypic resistance profilesCape VerdeAntiretroviral therapyjournal article10.1097/QAD.0000000000002431