RAS gene polymorphisms, classical risk factors and the advent of coronary artery disease in the Portuguese population

Freitas, Ana IMendonça, IsabelBrión, MariaSequeira, Miguel MReis, Roberto PCarracedo, AngelBrehm, António2019-03-062019-03-062008-07-17Freitas, A. I., Mendonça, I., Brión, M., Sequeira, M. M., Reis, R. P., Carracedo, A., & Brehm, A. (2008). RAS gene polymorphisms, classical risk factors and the advent of coronary artery disease in the Portuguese population. BMC cardiovascular disorders, 8(1), 15.http://hdl.handle.net/10400.26/28008Several polymorphisms within the renin-angiotensin system cluster of genes have been associated with the advent of coronary artery disease (CAD) or related pathologies. We investigated the distribution of 5 of these polymorphisms in order to find any association with CAD development and distinguish if any of the biochemical and behavioural factors interact with genetic polymorphisms in the advent of the disease.engAngiotensinogenCoronary Artery DiseaseGene FrequencyGenes, RASGenetic Predisposition to DiseasePeptidyl-Dipeptidase APolymorphism, GeneticPortugalRisk FactorsMadeiraRAS gene polymorphisms, classical risk factors and the advent of coronary artery disease in the Portuguese populationjournal article10.1186/1471-2261-8-15