Duarte, TiagoCaeiro, FernandoGóis, MárioMatos, AntónioViana, LenaVieira, CésarPaulos, JorgePaixão, PauloMatos, BrunoGermano, NunoNolasco, Fernando2025-09-082025-09-0820210872-0169http://hdl.handle.net/10400.26/58614SARS-Cov2 infection is a highly transmissible disease associated with serious pulmonary disease. Renal involvement is frequent and associated with poor prognosis; however, mechanisms of kidney injury are not well established. We present a SARS-Cov2 patient with severe acute kidney injury. Kidney biopsy findings revealed a pattern of acute tubular necrosis with isometric vacuolization of the proximal tubule. The interstitium and glomeruli were normal. Electronic microscopy showed multiple viral-like particles in both the glomeruli and proximal tubule. This case study shows how SARS-Cov 2 infection can result in different kinds of kidney lesion.engacute kidney injuryCOVID-19kidney biopsycontribution to journal10.32932/pjnh.2021.10.146