Correia, MagnaFreitas, JoãoVieira, RitaPerneta, FilipeBrazão, Luz2020-07-272020-07-272014Correia et al. Clinical and Translational Allergy 2014, 4(Suppl 3):P72http://hdl.handle.net/10400.26/32999Adverse reactions to drugs, Fixed Erythema (FE), correspond to 16-21% of all skin eruptions. This disease results in the development of one or more erythematous annular or oval, plaques as a result of systemic exposure to a drug. On reexposure relapse occurs in the same place, although new lesions may arise simultaneously in other areas. Any drug can cause FE. The physiopathology involves an allergic reaction (vasculitis).porflucanazoleanamnesisreaçºoes adversasvasculitisworking paper10.1186/2045-7022-4-S3-P72