Sousa, Ana CéliaMendonça, Maria I.Pereira, AndreiaGouveia, SaraFreitas, Ana I.Guerra, GraçaRodrigues, MarianaHenriques, EvaFreitas, SóniaBorges, SofiaPereira, DécioBrehm, AntónioPalma dos Reis, Roberto2019-03-062019-03-062017Sousa, A. C., Mendonça, M. I., Pereira, A., Gouveia, S., Freitas, A. I., Guerra, G., ... & Pereira, D. (2017). Synergistic Association of Genetic Variants with Environmental Risk Factors in Susceptibility to Essential Hypertension. Genetic testing and molecular biomarkers, 21(10), 625-631.http://hdl.handle.net/10400.26/28007Essential hypertension (EH) is a disease in which both environment and genes have an important role. This study was designed to identify the interaction model between genetic variants and environmental risk factors that most highly potentiates EH development.engCase-Control StudiesDiabetesEssential HypertensionGenetic Predisposition to DiseaseGenetic VariationMultifactor Dimensionality ReductionObesityPolymorphism, Single NucleotidePortugalRisk FactorsSterol Regulatory Element Binding Protein 1Gene-Environment InteractionMadeiraADD1journal article10.1089/gtmb.2017.0048