Percorrer por autor "Aissaoui, Oussama"
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- Biological therapy for oral cancer : immunotherapyPublication . Aissaoui, Oussama; Ribeiro, Carlos ZagaloMalignant tumors treatment, particularly in the case of oral cancer, presents a significant challenge within the realm of medical science. Current treatment modalities, ranging from surgical interventions to chemotherapy and radiation therapy, often yield mixed results. These approaches have their limitations, including the potential for tumor recurrence, non-resectable lesions, and the toxic side effects of radiotherapy and chemotherapy. As a result, there is a pressing need for innovative strategies to improve patient outcomes by reducing morbidity and mortality while enhancing their quality of life. Immunotherapy, a relatively new avenue in cancer treatment, offers promise as a complementary approach. It has the potential to mitigate the shortcomings of traditional treatments when used in conjunction with them. By harnessing the patient's immune system to enhance the specific immune response to cancer cells, immunotherapy holds significant potential. This promising approach gained widespread recognition when it was deemed the most significant scientific breakthrough by Science, due to its remarkable efficacy and innovation. Immunotherapy's role in the treatment of various malignant tumors, including oral cancer, is the central focus of this review. The review systematically explores the key elements involved, including the fundamental definition of immunotherapy. It delves into the intricate dynamics of the tumor microenvironment and the unique challenges associated with oral cancer, offering insights into the various techniques and strategies employed in immunotherapy. Furthermore, it highlights the challenges that researchers and clinicians face in this dynamic field, as well as the anticipated future developments. In essence, this review strives to illuminate the potential of immunotherapy as an invaluable addition to the arsenal of treatment options for oral malignant tumors. It emphasizes the importance of considering immunotherapy in the context of this particular malignancy, highlighting the ongoing challenges and the promising prospects that could substantially benefit patients confronting this debilitating disease.